Enkel Health

Hormones

What is SHBG?

controls how much free sex hormone you have

Unit
nmol/L
Sample
Serum
Fasting
No fasting needed
Turnaround
2 days

SHBG binds testosterone and estrogen in the blood and controls how much hormone is biologically available.

SHBG is affected by thyroid function, insulin resistance, liver disease, and hormonal medications. The value is central to interpreting sex hormone tests.

What does low SHBG mean?

Low SHBG appears with insulin resistance, overweight, and PCOS.

What does high SHBG mean?

High SHBG appears with hyperthyroidism, liver disease, hormone therapy, and in older men.

Panels that measure SHBG

  • Male Hormone Test Base
  • Female Hormone Test Plus
  • Male Hormone Test Plus
  • Fertility Test Plus
  • Performance Test Complete
  • Male Hormone Test Complete
  • Fertility Test Complete
  • Female Hormone Test Complete
  • Health Check Complete
  • Health Check Man

Launching in Stockholm in 2026.

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This is general information about the marker, not an assessment of your values and not medical advice. Last updated: August 2026.