Understanding the marker
This ratio is calculated from testosterone and SHBG, a protein that binds testosterone. It is different from measuring free or bioavailable testosterone.
The calculation requires results from the same collection and the laboratory's defined method. Both component values, symptoms and treatment context matter. The ratio alone does not diagnose hormone deficiency or excess, and it needs a verified reference for the specific calculation.
What does high Testosterone to SHBG ratio mean?
A high ratio means more testosterone relative to SHBG. The component values, symptoms and any treatment are needed for interpretation. It cannot identify a cause or establish hormone excess on its own.
What does low Testosterone to SHBG ratio mean?
A low ratio means less testosterone relative to SHBG. Its meaning depends on the individual component results and a verified reference for that calculation; it is not a direct measurement of free testosterone.
Reading
More markers in the same area
- PSA ratio (free to total)PSA result
- Estradiola form of the hormone estrogen
- Progesteronea hormone that can support evidence of recent ovulation
- FSHa hormone signal to the ovaries or testes
- LHa hormone signal involved in reproductive function
- Testosteronea hormone involved in reproductive and muscle function
This is general information about the marker, not an assessment of your values and not medical advice. Last updated: October 2026.
