Testosterone to SHBG ratio

testosterone compared with its binding protein

Sample
Serum
Fasting
10 hours

Understanding the marker

This ratio is calculated from testosterone and SHBG, a protein that binds testosterone. It is different from measuring free or bioavailable testosterone.

The calculation requires results from the same collection and the laboratory's defined method. Both component values, symptoms and treatment context matter. The ratio alone does not diagnose hormone deficiency or excess, and it needs a verified reference for the specific calculation.

This is general information about the marker, not an assessment of your values and not medical advice. Last updated: October 2026.

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